Personal information
Xiaoyun Su, Ph. D., Professor. In 2000, he received a bachelor's degree from Southwest Agricultural University. In 2003, he received a master's degree from Nanjing Agricultural University. In 2010, he received a doctor's degree from the Institute of Microbiology, Chinese Academy of Sciences. From 2009 to 2012, he conducted postdoctoral research at the University of Illinois at Champaign in the United States, and from 2012 to 2014, he worked in Agency for Science,Technology and Research. From 2014 to 2020, he worked in the Feed Research Institute of the Chinese Academy of Agricultural Sciences, and from 2020 to now, he has worked in the Institute of Animal Sciences in the Chinese Academy of Agricultural Sciences.
Research interests
Prof. Su is interested in the following areas:
Modulation of the gut microbiota by designed enzymes and microbes;
Enzymatic detoxification of mycotoxins;
Developing filamentous fungi as a protein-expression platform.
Projects under research
1. Key International Cooperation Projects of the National Natural Science Foundation of China
2. National Key R&D Plan
Representative Papers and Patents
Patents
1. A method for improving the cellulase-producing ability of Trichoderma reesei, , ranking 2nd (April 2019)
2. Mutants of a bifunctional xylanase/cellulase with improved specificity on cellulase substrate and its codig gene and application , ranking No.1 (November 2017)
3. Thermotable C. bescii enzymes, (Patent No. US9765371), ranked 2nd (April 2019)
Paper
1. Xiaoyun Su, Zhenzhen Hao, Bin Yao. Translocation of health-promoting enzymes across the gut barrier. Trends Endocrinol Metab. 2023,34(5):257-259
2. Xiaoyun Su, Bin Yao.Exploiting enzymes as a powerful tool to modulate the gut microbiota. Trends Microbiol. 2022 30(4):314-317
3. Yindi Chu , Tao Tu , Leena Penttinen, Xianli Xue, Xiaoyu Wang , Zhuolin Yi , Li Gong, Juha Rouvinen , Huiying Luo, Nina Hakulinen, Bin Yao, Xiaoyun Su. Insights into the roles of non-catalytic residues in the active site of a GH10 xylanase with activity on cellulose. J Biol Chem. 2017,292(47):19315-19327.
4. Xiaolu Wang‡, Xing Qin‡, Zhenzhen Hao, Huiying Luo, Bin Yao*, Xiaoyun Su*. Degradation of four major mycotoxins by eight manganese peroxidases in presence of a dicarboxylic acid. Toxins 2019,11:566
5. Fei Gao, Zhenzhen Hao, Xianhua Sun, Lina Qin, Tong Zhao, Weiquan Liu, Huiying Luo, Bin Yao*, Xiaoyun Su*. A versatile system for fast screening and isolation of Trichoderma reesei cellulase hyperproducers based on DsRed and fluorescence-assisted cell sorting. Biotechnology for Biofuels, 2018, 11:261
6. Xianhua Sun, Xuhuan Zhang, Huoqing Huang, Yuan Wang, Tao Tu, Yingguo Bai, Yaru Wang, Jie Zhang, Huiying luo, Bin Yao*, and Xiaoyun Su*. Engineering the cbh1 promoter of Trichoderma reesei for enhanced protein production by replacing the binding sites of a transcription repressor ACE1 to those of the activators. Journal of Agricultural and Food Chemistry.
7. Xiaolu Wang, Yingguo Bai, Huoqing Huang, Tao Tu, Yuan Wang, Yaru Wang, Huiying Luo, Bin Yao*, Xiaoyun Su*. Degradation of aflatoxin b1 and zearalenone by bacterial and fungal laccases in presence of structurally defined chemicals and complex natural mediators. Toxins 2019,11:609.
8. Xiaolu Wang, Bin Yao* and Xiaoyun Su*. Linking enzymatic oxidative degradation of lignin to organics detoxification. International Journal of Molecular Sciences 2018, 19:3373
9. Xing Qin, Xiaoyun Su*, Huiying Luo, Rui Ma, Bin Yao*, Fuying Ma*. Deciphering lignocellulose deconstruction by the white rot fungus Irpex lacteus based on genomic and transcriptomic analyses. Biotechnology for Biofuels, 2018,11:58
10. Xianhua Sun, Xianli Xue, Mengzhu Li, Fei Gao, Zhenzhen Hao, Huoqing Huang, Huiying Luo, Lina Qin,*, Bin Yao,*, and Xiaoyun Su*. Efficient coproduction of mannanase and cellulase by the transformation of a codon-optimized endomannanase gene from Aspergillus niger into Trichoderma reesei. Journal of Agricultural and Food Chemistry. 2017,65:11046-11053
Contact information
Tel: 010-62599910 E-mail：suxiaoyun@caas.cn