Personal Information
Ran Di
Ph.D / Associate Professor
Major: Animal Genetics and Breeding
Research Area: Animal Genetics and Breeding
Tel: 15011356508; 010-62816001
E-mail： diran@caas.cn
Personal information
PhD Ran Di, Associate Professor, Master Supervisor. She received her BSc degree in Animal Medicine from Qingdao Agricultural University (2002); and received her PhD degree in Animal Genetics & Breeding from Chinese Academy of Agricultural Sciences (2008). She is a key member in mutton sheep and goat genetics and breeding team. She is mainly engaged in animal genetic evolution, evaluation of sheep germplasm resources, molecular mechanism analysis of important traits and breeding of new breeds of mutton sheep. A member of the council, Sheep and goat branch, Chinese Association of Animal Science and Veterinary Medicine (CAAV). She has won the Travel Bursary Award, 31st International Society for Animal Genetics Conference, in Amsterdam, Netherlands.
Research area & Awards
Since 2008, she has been mainly engaged in animal genetic evolution, evaluation of sheep germplasm resources, molecular mechanism analysis of important traits and breeding of new breeds of mutton sheep. She has published more than 200 papers in many journals, such as Animal Genetics, BMC Genomics, Frontiers in Genetics, Biology, Reproduction Fertility and Development, Journal of Animal Breeding and Genetics, including 18 papers as first author and 30 papers as corresponding author. She was authorized 15 national invention patents, including four as the top two finishers. She is the editors of SCI journals such as Frontiers in Genetics, Biology and Frontiers in Veterinary Science.
She participated in the breeding of new breeds of mutton sheep-Luzhong mutton sheep, and a new breed certificate was obtained in 2020. She won the second prize of the Tianjin Science and Technology Progress Award, ranked fourth, 2022, “Precise uncovering of high fecundity traits and the integrated application of supporting technologies for industrialization in meat sheep” and the third prize of the Beijing Science and Technology Award, ranked seventh, 2013, “Screening and application of molecular genetic markers involved in reproductive traits of sheep and goat”
Ongoing Research Projects
(1) International Cooperation and Exchange Program of National Natural Science Foundation (NSFC) of China, (31861143012), “Study on the specific molecular genetic mechanism of prolific trait in African and Middle Eastern sheep”.
(2) National Natural Science Foundation of China, (32272838), “Mechanism of FecB mutation increasing ovulation number by enhancing the binding of FKBP1A and BMPR1B”.
(3) National Key R&D Program of China, (2021YFD1300904), “Breeding and expanding propagation of new sheep breeds and lines”.
(4) Agricultural Science and Technology Innovation Project of China, (ASTIP-IAS13), “Mutton sheep and goat genetics and breeding”.
Patents & Publications
Patents: A miRNA and its specific primers and methods for detection (ZL 201410740648.2); A SNP molecular marker for predicting prolificacy in sheep and its application (ZL 201811169521.4); A SNP molecular marker related to sheep prolific traits and its detection kit and application (ZL 201811353677.8); A SNP molecular marker for predicting prolificacy in sheep and its application (ZL 201811169521.4).
Di R(#), Zhang R S(#), Mwacharo J M, Wang X Y, He X Y, Liu Y F, Zhang J L, Gong Y M, Zhang X S(*), Chu M X(*). Characteristics of piRNAs and their comparative profiling in testes of sheep with different fertility. Frontiers in Genetics, 2022,13:1078049.
Di R(#), Fan Y K(#), He X Y, Liu Q Y, Wang X Y, Gong Y M, Mwacharo J M, Wei C H, Liu Y F(*), Chu M X(*). Epigenetic regulation of miR-25 and lnc107153 on expression of seasonal estrus key gene CHGA in sheep. Biology, 2023, 12:250.
Tao L(#), He X Y(#), Wang F Y, Pan L X, Wang X Y, Gan S Q, Di R(*), Chu M X(*). Identification of genes associated with litter size combining genomic approaches in Luzhong mutton sheep. Animal Genetics, 2021, 52(4):545-549.
Tao L(#), Liu Y F(#), Zhang H, Li H Z, Zhao F P, Wang F Y, Zhang R S, Di R(*), Chu M X(*). Genome-wide association study and inbreeding depression on body size traits in Qira black sheep (Ovis aries). Animal Genetics, 2021, 52(4):560-564.
Di R(#), Liu Q Y(#), Song S H#, Tian D M#, He J N, Ge Y, Wang X Y, Hu W P, Mwacharo J M, Pan Z Y, Wang J D, Ma Q, Cao G L, Jin H H, Liang X J(*), Chu M X(*). Expression characteristics of pineal miRNAs at ovine different reproductive stages and the identification of miRNAs targeting the AANAT gene. BMC Genomics, 2021, 22(1):217.
He X(#), Liu Q(#), Li X, Guo X, Wang X, Hu W, Di R(*), Chu M X(*). Molecular cloning and epigenetic change detection of kiss1 during seasonal reproduction in Chinese indigenous sheep. Reprod Fertil Dev, 2018, 30(5):734-743.
Di R(#), He J N(#), Song S H(#), Tian D M(#), Liu Q Y, Liang X J, Ma Q, Sun M, Wang J D, Zhao W M, Cao G L, Wang J X, Yang Z M, Ge Y, Chu M X(*). Characterization and comparative profiling of ovarian microRNAs during ovine anestrus and the breeding season. BMC Genomics, 2014, 15(1):899.
Di R, Farhad Vahidi S M, Ma Y H(*), He X H, Zhao Q J, Han J L, Guan W J, Chu M X, Sun W, Pu Y P. Microsatellite analysis revealed genetic diversity and population structure among Chinese cashmere goats. Animal Genetics, 2011, 42(4):428-431.
Tao L(#), He X Y(#), Wang F Y, Zhong Y J, Pan L X, Wang X Y, Gan S Q, Di R(*), Chu M X(*). Luzhong mutton sheep: inbreeding and selection signatures. Journal of Animal Science and Technology, 2020, 62(6):777-789.