1）饲料养分效价工业化评定技术的创制与应用

立足于国家饲料粮减量替代及饲料资源高效利用的战略需求，创建单胃动物饲料养分效价工业化评定方法及技术平台，重点围绕饲料营养价值评定、饲用价值分析系统构建、饲料养分高效利用及其调控机制开展研究，并通过技术集成与企业合作，开发实用技术。

2）矿物元素营养研究及应用

针对畜禽养殖中矿物元素利用率低及过度排放污染环境等问题，系统、深入开展畜禽饲料矿物元素营养价值评定、营养需要量和营养代谢及调控机制研究，精准满足畜禽矿物元素营养需求，优化其功能性调控作用，节约矿物质饲料资源。

3）肉鸡营养与环境

不同理化环境（热、光和有害气体）下肉鸡生理和营养代谢动态变化及其分子机制研究；肉仔鸡动态营养需要和日粮配制技术研究；种母鸡—胚胎—肉仔鸡营养传递及其环境和营养调控技术研究。

4）酶与饲料资源开发

在新型蛋白酶、产非淀粉多糖酶曲霉菌及产漆酶木腐菌的开发与应用方面，取得了多项突破性成果，同时以解脂耶氏酵母为底盘细胞构建了高产类胡萝卜素平台，为高效畜禽健康养殖和功能性畜产品生产提供了重要支撑条件。

1. 科技奖励与成果转化

中国专利奖优秀奖：单胃动物仿生消化系统及基于该系统模拟单胃动物消化的方法。

温氏食品集团股份有限公司科技进步奖特等奖：基于仿生消化法的饲用原料黄鸡代谢能值动态数据库的建立及应用。

研发的单胃动物仿生消化技术和设备已在89家国内大型科企单位（其中上市企业27家）推广应用，覆盖的饲料产量超过1.3亿吨，约占中国工业饲料产量的40%；2025年实现技术出口至新加坡、巴西和比利时等养殖业发达国家。累计获得中国发明专利10余项，其中专利许可/转让3项。2022年列为农业农村部豆粕减量替代典型案例技术，2023年被列为中国农业科学院“科技创新工程十年总结与展望”标志成果。

2. 代表性论文

（1）Dandan Ma, Minhong Zhang^*, Jinghai Feng. Gut microbiota alleviates intestinal injury induced by extended exposure to light via inhibiting the activation of NLRP3 inflammasome in broiler chickens. International Journal of Molecular Sciences, 2024, 25:6695.

（2）Dandan Ma, Shaoshuai Zhang, Minhong Zhang^*, Jinghai Feng. Dietary tryptophan alleviates intestinal inflammation caused by long photoperiod via gut microbiota derived tryptophan metabolites-NLRP3 pathway in broiler chickens. Poultry Science, 2024, 103:103509.

（3）Mengjie Xu, Xin Zhao, Miao Yu, Guangju Wang, Jinghai Feng, Minhong Zhang^*. The amino acid pattern and dynamics of body protein, body fat deposition in male and female broilers under different temperatures Poultry Science, 2024, 103: 103525.

（4）Xiaomeng Ye, Feng Zhao^*, Yuming Wang, Jingjing Xie, Hu Zhang, Renna Sa, Zheng Sun, Xiudong Liao, Lin Lu, Jinghai Feng. Predicting metabolizable energy of soybean meal and rapeseed meal from chemical composition in broilers of different ages. Poultry Science, 2024, 103:103915.

（5）Xiaoran Li, Chong Wang, Shunying Li, Liyang Zhang, Xiudong Liao, Lin Lu^*. Low protein diet influences mineral absorption and utilization in medium-growing yellow-feathered broilers from 1 to 30 days of age. Poultry Science, 2024, 103:104512.

（6）Xiudong Liao^#, Liang Huang, Xugang Luo, Liyang Zhang, Lin Lu, Dezhao Luo, and Wei Lu. Distribution and health risk of chromium in wheat grains at the national scale in China. Journal of Hazardous Materials, 2024, 474:134846.

（7）Ying Zhang, Youyou Liu, Songjun Jiao, Yuming Wang, Renna Sa, Feng Zhao, Jingjing Xie^*. Short-term supplementation with uncoated and encapsulated Enterococcus faecium affected growth performance, gut microbiome and intestinal barrier integrity in broiler chickens. Poultry Science, 2024, 103:103808.

（8）Mengli Zheng, Yan Bai, Yingxia Sun, Jing An, Qinghua Chen, Tieying Zhang^*. Effects of different proteases on protein digestion in vitro and in vivo and growth performance of broilers fed corn-soybean meal diets. Animals, 2023, 13:1746.

（9）Qingtao Gao, Feng Zhao, Ya Wang, Hu Zhang, Jiangtao Zhao, Lixiang Gao, Xuelan Liu, Yuming Wang^*. Predicting energetic values of cereal grains and byproducts using a computer-controlled simulated digestion system for growing pigs. Animal Feed Science and Technology, 2023, 306:115809.

（10）Zhongyuan Du, Lixiang Gao, Yuming Wang, Jingjing Xie, Shuli Zeng, Jiangtao Zhao, Renna Sa, Feng Zhao^*. A comparative study on in vitro and in vivo stomach–small intestinal and large intestinal digestion of plant protein meals in growing pigs. Journal of Animal Science, 2023, 101:skad170.

（11）Yuming Wang^#, Liting Yin, Hu Zhang, Ke Li, Dailin Li, Feng Zhao^*. Accuracy of predicting metabolizable energy from in vitro digestible energy determined with a computer-controlled simulated digestion system in feed ingredients for ducks. Animal Nutrition, 2022, 8:52-60.

（12）Xiudong Liao^#, Guoqing Liu, Guangming Sun, Xiaoming Sun, Tao Liu, Lin Lu, Liyang Zhang, Minhong Zhang, Yanli Guo, Xugang Luo. Determination of optimal dietary selenium levels by full expression of selenoproteins in various tissues of broilers. Animal Nutrition, 2021, 7:1133-1144.

（13）Sumei Cao, Tingting Li, Yuxin Shao, Liyang Zhang, Lin Lu, Rijun Zhang, Shuisheng Hou, Xugang Luo, Xiudong Liao^*. Regulation of bone phosphorus retention and bone development possibly by related hormones and local bone-derived regulators in broiler chicks. Journal of Animal Science and Biotechnology, 2021, 12:88.

（14）Qiujue Wu, Xiaochuan Zheng, Tian Wang, Tieying Zhang^*. Effect of dietary oridonin supplementation on growth performance, gut health, and immune response of broilers infected with Salmonella pullorum. Irish Veterinary Journal, 2018, 71:16.

（15）Tieying Zhang^#, JL Liu, JL Zhang, N Zhang, X Yang, HX Qu, L Xi, JC Han. Effects of dietary zinc levels on the growth performance, organ zinc content, and zinc retention in broiler chickens. Brazilian Journal of Poultry Science, 2018, 20:127-132.