科研队伍-专家队伍-详情

专家队伍

Expert Team

个人信息

汤新明，1989年9月生，山东济宁人，博士，副研究员。2012年获山东农业大学学士学位；2018年获中国农业大学博士学位；2018年7月至2020年6月中国农业科学院北京畜牧兽医研究所兽医学科博士后流动站从事博士后研究工作；2020年7月至今在中国农业科学院北京畜牧兽医研究所物疫病防控创新团队工作。主要从事动物疫病病原学、免疫学、诊断和分子流行病学研究。

研究方向和成果

主要从事动物载体疫苗研制和病原发育调控的研究工作。开展动物寄生虫病原的反向遗传操作平台、载体疫苗设计与优化、动物免疫应答检测平台和载体疫苗免疫效果评价以及动物病原（球虫）发育调控机理的研究等工作。发表论文30余篇，其中SCI论文20篇；授权发明专利6项。

在研项目

1.国家自然科学基金青年基金项目，项目主持人（编号：31902295）

2.北京市自然科学基金青年基金项目，项目主持人（编号：6204045）

代表性论文和专利

1.Tang Xinming, Suo Jingxia, Liang Lin, Duan Chunhui, Hu Dandan, Gu Xiaolong, Yu Yonglan, Liu Xianyong, Cui Shangjin*, Suo Xun*. Genetic modification of the protozoan Eimeria tenella using the CRISPR/Cas9 system. Veterinary Research. 2020. 51(1):41.

2.Tang Xinming, Liu Xianyong, Suo Xun*. Towards innovative design and application of recombinant Eimeria as a vaccine vector. Invited review. Infection and Immunity. 2020. 9:88.

3.Tang Xinming, Wang Chaoyue, Liang Lin, Hu Dandan, Zhang Sixin, Duan Chunhui, Suo Jingxia, Liu Xianyong, Suo Xun, Cui Shangjin*. Co-immunization with two recombinant Eimeria tenella lines expressing immunoprotective antigens of E. maxima elicits enhanced protection against E. maxima infection. Parasites & Vectors. 2019. 12(1):347.

4.Tang Xinming, Suo Jingxia, Li Chao, Du Mengze, Wang Chaoyue, Hu Dandan, Duan Chunhui, Liu Xianyong, Yanli Lyu, Suo Xun*. Transgenic Eimeria tenella expressing profilin of E. maxima elicits enhanced protective immunity and alters gut microbiome of chickens. Infection and Immunity. 2018. 9:86.

5.Tang Xinming, Liu Xianyong, Yin Guangwen, Suo Jingxia, Tao Geru, Zhang Sixin, Suo Xun*. A novel vaccine delivery model of the apicomplexan Eimeria tenella expressing E. maxima antigen protects chickens against infection of the two parasites. Frontiers in Immunology. 2018. 8:1982.

6.Tang Xinming, Yin Guangwen, Qin Mei, Tao Geru, Suo Jingxia, Liu Xianyong, Suo Xun*. Transgenic Eimeria tenella as a vaccine vehicle: expressing TgSAG1 elicits protective immunity against Toxoplasma gondii infections in chickens and mice. Scientific Reports. 2016. 6:29379.

7.Tang Xinming, Liu Xianyong, Tao Geru, Qin Mei, Yin Guangwen, Suo Jingxia, Suo Xun*. “Self-cleaving” 2A peptide from porcine teschovirus-1 mediates cleavage of dual fluorescent proteins in transgenic Eimeria tenella. Veterinary Research. 2016. 47:68.

8.Li Zhuoran, Tang Xinming（co-first author）, Suo Jingxia, Qin Mei, Yin Guangwen, Liu Xianyong, Suo Xun*. Transgenic Eimeria mitis expressing chicken interleukin 2 stimulated higher cellular immune response in chickens compared with the wild-type parasites. Frontier in Microbiology. 2015. 6:533.

联系方式

联系电话：010-62813876 E-mail：tangxinming@caas.cn

（简历更新时间 2022-09-30）