个人信息

赵勇，博士，教授，博士生导师。2000年获得山东农业大学农学学士学位；2004年获得中国农业科学院理学硕士学位（生物化学与分子生物学）；2008年获美国South Dakota State University（南达科塔州立大学）药学博士学位。2008年 - 2013年在美国Michigan State University（密歇根州立大学）从事博士后研究工作。2013年 - 2021年青岛农业大学教授。 2020年入选中国农业科学院青年英才计划所级人才，2021年获得“颐和”青年成就奖，现担任家畜营养与调控创新团队科研骨干专家。主要从事营养与肠道菌群调控精子发生及雄性动物繁殖力的研究。中国动物学会细胞和分子显微技术分会理事，中国动物学会生殖生物学分会理事，澳大利亚Murdoch大学兼职教授。

研究方向与成果

聚焦动物精子发生及雄性动物繁殖健康近十年，确立了肠-睾丸轴并围绕其对精子发生的调控作用、环境因子危害精子发生、肠道菌群修复挽救雄性动物繁殖力等方面开展工作，在国内外知名学术期刊发表论文80篇，近五年以第一或通讯作者在Gut（2篇；IF="23.1）、Microbiome（IF="14.6）、Theranostics（IF="11.5）、Mucosal Immunology（IF="7.3）等本领域权威期刊（SCI收录）发表论文31篇。团队研究成果被提名中国农科院2020年“年度十大科技进展”。

在研项目

1.国家自然科学基金委面上项目“乙酰胆碱M5受体通过调节细胞间连接来调控精子发生的机制”（编号：32070536）

2.国家自然科学基金委面上项目“NH3/H2S暴露损害精子发生及跨代遗传的lncR-A调节机制”（编号：31772408）

代表性论文和专利

1.    Pengfei Zhang (#), Yanni Feng (#), Lan Li (#), Wei Ge, Shuai Yu, Yanan Hao, Wei Shen, Xiao Han, Dongxue Ma, Shen Yin, Yu Tian, Lingjiang Min, Zhongyi Sun, Qingyuan Sun, Hongfu Zhang*, Yong Zhao*. Improvement in sperm quality and spermatogenesis following fecal microbiota transplantation from alginate oligosaccharide dosed mice. Gut 2021; 70(1): 222-225. doi: 10.1136/gutjnl-2020-320992.  (IF="23.059)

2.    Cong Zhang, (#) Bohui Xiong (#), Liang Chen (#), Wei Ge, Shen Yin, Yanni Feng, Zhongyi Sun, Qingyuan Sun, Yong Zhao*, Wei Shen*, Hongfu Zhang*. Rescue of male fertility following fecal microbiota transplantation from alginate oligosaccharide dosed mice. Gut 2020; doi: 10.1136/gutjnl-2020-323593.  (IF="23.059)

3.    Pengfei Zhang, Jing Liu, Bohui Xiong, Cong Zhang, Beining Kang, Yishan Gao, Zengkuan Li, Wei Ge, Shunfeng Cheng, Yanan Hao, Wei Shen, Shuai Yu, Liang Chen, Xiangfang Tang, Yong Zhao*, Hongfu Zhang*. Microbiota from alginate oligosaccharide dosed mice successfully mitigated small intestinal mucositis. Microbiome 2020; 8(1):112. doi:10.1186/s40168-020-00886-x. (IF="14.65)

4.   Yong Zhao, Pengfei Zhang, Wei Ge, Yanni Feng, Lan Li, Zhongyi Sun, Hongfu Zhang*, Wei Shen*. Alginate oligosaccharides improve germ cell development and testicular microenvironment to rescue busulfan disrupted spermatogenesis. Theranostics 2020;10(7): 3308-3324. doi: 10.7150/thno.43189. (IF="11.556)

5.    Yong Zhao (#), Yanni Feng (#), Ming Liu (#), Liang Chen, Qingshi Meng, Xiangfang Tang, Shukun Wang, Lei Liu, Lan Li, Wei Shen*, Hongfu Zhang*. Single-cell RNA sequencing analysis reveals alginate oligosaccharides preventing chemotherapy- induced mucositis. Mucosal Immunol. 2020; 13(3): 437-448. doi: 10.1038/s41385-019-0248-z. (IF="7.313)

6.    Xiao Han, Pengfei Zhang, Wei Shen, Hongfu Zhang, Cong Zhang, Xiangping Ma, Xiaowei Yan, Bohui Xiong, Wei Ge, Lan Li, Shen Yin, Zhaojia Ge, Lingjiang Min, Zhongyi Sun, Qingyuan Sun, Yong Zhao*. Muscarinic Acetylcholine Receptor M5 Involved in Spermatogenesis through the Modification of Cell-Cell Junctions. Reproduction 2021; 162(1):47-59. (IF="3.906).

7.    Dongxue Ma (#), Pengfei Han  (#), Mingji Song (#), Hongfu Zhang, Wei Shen, Guian Huang, Minghui Zhao, Qingyuan Sun, Yong Zhao*, Lingjiang Min*. β-carotene rescues busulfan disrupted spermatogenesis through elevation in testicular antioxidant capability. Front Pharmacol. 2021; 12:593953. (IF="5.81)

8.    Huatao Li, Pengfei Zhang, Yong Zhao*, Hongfu Zhang*. Low Doses of Carbendazim and Chlorothalonil Synergized to Impair Mouse Spermatogenesis through Epigenetic Pathways. Ecotoxicol Environ Saf. 2020;188:109908. doi: 10.1016/j.ecoenv. 2019.109908. (IF="6.291)

9.    Pengfei Zhang (#), Yong Zhao (#), Hongfu Zhang, Jing Liu, Yanni Feng, Shen Yin, Shunfeng Cheng, Xiaofeng Sun, Lingjiang Min, Lan Li, Wei Shen*. Low Dose Chlorothalonil Impairs Mouse Spermatogenesis through the Intertwining of Estrogen Receptor Pathways with Histone and DNA Methylation. Chemosphere 2019; 230:384-395. (IF="5.778)

10.    Jing Liu, Pengfei Zhang, Yong Zhao, Hongfu Zhang*. Low Dose Carbendazim Disrupts Mouse Spermatogenesis Might Be through Estrogen Receptor Related Histone and DNA Methylation. Ecotoxicol Environ Saf. 2019;176:242-249. (IF="4.872)

联系方式

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（简历更新时间 2022-09-30）