个人信息

王加启，男，1967年6月生，博士，研究员，博士生导师。1993年获北京农业大学畜牧学博士学位。1993年起至今在中国农业科学院北京畜牧兽医研究所从事奶牛营养与牛奶质量安全研究。1994年12月-1995年10月在英国Rowett研究所做博士后研究。现任中国农业科学院北京畜牧兽医研究所奶产品质量安全与风险评估团队首席科学家，国家百千万人才工程第一、二层次人选，兼任国务院食品安全委员会专家委员会委员、全国畜牧业标准化技术委员会委员、食品安全国家标准专家委员会委员、Journal of Dairy Science编委等。

研究方向和成果

1993年以来，带领团队从反刍动物营养研究起步，逐渐聚焦为“奶牛营养—牛奶品质形成—牛奶功能评价”，形成鲜明的“品质营养学”研究特色。主要研究成果有：揭示我国奶牛养殖模式中乳脂肪和乳蛋白偏低的内在机理，创建提高乳脂肪和乳蛋白的奶牛营养调控关键技术，突破了制约奶牛生产优质乳的技术瓶颈；构建我国奶产品质量安全风险评估与营养品质评价数据库，提出优质奶产自本土奶的科学理念，为我国奶业由数量型增长向安全优质转型升级提供了强有力技术支撑。

研究成果先后获得国家科技进步二等奖3项（1999年，2012年，2020年）；2019年获神农中华农业科技奖创新团队奖，2012年获第十四届中国专利优秀奖。

在研项目

1. “十四五”国家重点研发计划项目“奶业全产业链高效优质生产关键技术”（编号：2022YFD1301000）

2. “十四五”现代农业产业技术体系（奶牛）岗位科学家（编号：CARS-36）3. 中国农业科学院科技创新工程项目“奶产品质量与风险评估创新团队”首席科学家项目（编号：ASTIP-IAS12）

代表性论文和专利

以第一或通讯作者发表SCI论文116篇、中文论文50篇；以主编身份出版书籍10余部；以第一完成人制定国家标准7项；获发明专利20件，其中1件获中国专利优秀奖。

近期主要代表作：

1. Liu Sijia, Moon Christina D, Zheng Nan, Huws Sharon, Zhao Shengguo*, Wang Jiaqi*. Opportunities and challenges of using metagenomic data to bring uncultured microbes into cultivation. Microbiome. 2022, 10:76.

2. Liu Sijia, Yu Zhongtang, Zhong Huiyue, Zheng Nan, Huws Sharon, Wang Jiaqi*, Zhao Shengguo*. Functional gene-guided enrichment plus in situ microsphere cultivation enables isolation of new crucial ureolytic bacteria from the rumen of cattle. Microbiome. 2023, 11:76.

3. Zhong Huiyue, Yu Wenjing, Wang Min, Lin Bo, Sun Xuezhao, Zheng Nan, Wang Jiaqi*, Zhao Shengguo*. Sodium butyrate promotes gastrointestinal development of preweaning bull calves via inhibiting inflammation, balancing nutrient metabolism, and optimizing microbial community functions. Animal Nutrition. 2023,14: 88-100.

4. Du Bingyao, Meng Lu, Liu Huimin, Zheng Nan, Zhang Yangdong, Zhao Shengguo, Li Ming, Wang Jiaqi*. Diversity and proteolytic activity of Pseudomonas species isolated from raw cow milk samples across China. Science of the Total Environment. 2022, 838:156832.

5. Liu Kaizhen, Zhang Yangdong, Huang Guoxin, Zheng Nan, Zhao Shengguo, Wang Jiaqi*. Ruminal bacterial community is associated with individual variations of total milk solid content in Holstein lactating cows. Animal Nutrition. 2022,9:175-183.

6. Liu Kaizhen, Zhang Yangdong *, Yu Zhongtang, Xu Qingbiao, Zheng Nan, Zhao Shengguo, Huang Guoxin, Wang Jiaqi*. Ruminal microbiota–host interaction and its effect on nutrient metabolism. Animal Nutrition. 2021,7(1):49-55.

7. Hailemariam Samson. Zhao Shengguo*, He Yue, Wang Jiaqi*. Urea transport and hydrolysis in the rumen: A review. Animal Nutrition. 2021,7(4): 989-996.

8. Chen Meixia, Chen Chongchong, Wang Fengen, Wen Fang, Li Ming, Zheng Nan, Wang Jiaqi*. A rapid UPLC method with optimized sample preparation procedures for determination of furosine in milk. Journal of Food Composition and Analysis. 2020, 92: 103571.

9. Zhang Xiaoyin, Zhao Shengguo, He Yue, Zheng Nan, Yan Xianghua, Wang Jiaqi*. Substitution of residues in UreG to investigate UreE interactions and nickel binding in a predominant urease gene cluster from the ruminal metagenome. International Journal of Biological Macromolecules. 2020, 161: 1591-1601.

10. Dong Lei, Meng Lu, Liu Huimin, Wu Haoming, Hu Haiyan, Zheng Nan, Wang Jiaqi*, Martine Schroyen. Effect of therapeutic administration of β-lactam antibiotics on the bacterial community and antibiotic resistance patterns in milk. Journal of Dairy Science. 2021,104: 7018-7025.

11. Zhou Xuewei, Zheng Nan, Sun Chuanyou, Wang Jiaqi*, Helene Soyeurt. Relationships between Pb, As, Cr, and Cd in individual cows’ milk and milk composition and heavy metal contents in water, silage, and soil. Environmental Pollution. 2019, 255(Pt 2): 113322.

12. Du Bingyao, Wen Fang, Zhang Yangdong, Zheng Nan, Li Songli, Li Fadi, Wang Jiaqi*. Presence of tetracyclines, quinolones, lincomycin and streptomycin in milk. Food Control. 2019, 100:171-175.

13. Guo Xiaodong, Wen Fang, Qiao Qinqin, Zheng Nan, Matthew Saive, Marie-Laure Fauconnier, Wang Jiaqi*. A Novel Graphene Oxide-Based Aptasensor for Amplified Fluorescent Detection of Aflatoxin M1 in Milk Powder. Sensors. 2019,19(18):3480.

14. Luo Chaochao, Zheng Nan, Zhao Shengguo, Wang Jiaqi*. Sestrin2 Negatively Regulates Casein Synthesis through the SH3BP4-mTORC1 Pathway in Response to AA Depletion or Supplementation in Cow Mammary Epithelial Cells. Journal of Agricultural and Food Chemistry. 2019, 67(17):4849-4859.

15. Zheng Nan, Gao Yanan, Liu Jia, Wang Haiwei, Wang Jiaqi*. Individual and combined cytotoxicity assessment of zearalenone with ochratoxin A or α-zearalenol by full factorial design. Food Science and Biotechnology. 2018, 27(1):251-259.

16. Huang Liangce, Zheng Nan, Zheng Baoqin, Wen fang, Cheng Jianbo, R W Han, Xu Xiaomin, Li Songli, Wang Jiaqi*. Simultaneous determination of aflatoxin M-1, ochratoxin A, zearalenone and alpha-zearalenol in milk by UHPLC-MS/MS(ESI高被引论文). Food Chemistry. 2014, 146:242-249.

联系方式

联系电话： 010-62816069    E-mail: wangjiaqi@caas.cn

（简历更新时间 2023年09月30日）