Hongfei Zhu
Source: Author: Date:2014-11-29
Name: Hongfei Zhu
Major：Preventive Veterinary Medicine
Position：Research fellow
Phone Number：010-62819061
Fax：010-62819061
E-mail：bioclub@vip.sina.com
Hongfei ZHU was born in 1965, in Lianshui County of Jiangsu Province. He got his Doctor Degree in Preventive Veterinary Medicine, and is now Research Fellow and Doctoral Supervisor in the Institute of Animal Sciences of Chinese Academy of Agricultural Sciences. In the meantime, he serves as the Director of Biological Products Engineering Center of CAAS, evaluation expert for the National Science and Technology Award as well as the National 863 Program in the field of modern agricultural technology, Member of the first session National Expert Committee on Animal Epidemic Prevention Epidemiology, Deputy Dead of veterinary public health expert group, evaluation expert of the fifth evaluation committee for veterinary drugs of the MOA, and the chief scientist in the Project “Molecular diagnostic technology research against animal diseases and product development” in the field of modern agriculture technology of the Twelfth Five-year Plan National 863 Program.
Research of interests：
Animal immune adjuvants and novel vaccine research and development,
Major animal epidemics and exotic animal diseases prevention and control
On-going Research Projects
"Molecular diagnostic technology research against animal diseases and product development ", Project from the Twelfth Five-year National 863 Program;
Nonprofit industry research project "brucellosis, bovine tuberculosis prevention and control technology research";
Nonprofit industry special research project "Rapid diagnosis methods for pet di--seases, vaccine development and technology demonstration ";
Animal disease surveillance, prevention and control, Project from the Ministry of Agriculture
3. Major Research Achievements and Awards
Presided over the completion of the project "genetic engineering of subunit vaccine of sheep hydatid disease", which obtained the first class of new veterinary drugs from the Ministry of Agriculture (1st person involved);
The project "Marek's disease trivalent live vaccine" obtained the second class of registration certificate for new veterinary drugs from the Ministry of Agriculture (2nd person involved)
Presided over the drafting of the "Diagnostic techniques of virulent infection of Marek's disease in chicken" promulgated as the agricultural industry standard by the Ministry of Agriculture in January 2005 (2nd person involved)
Obtained three national invention patents:
Genetically engineered recombinant of CpG DNA as livestock vaccine adjuvant (ZL200310106226.1),
Preparation of poultry vaccine adjuvant containing CpG DNA via PCR (ZL2003 10106227.6),
Large-scale plasmid DNA purification process (ZL200510090721.7)
4. Selected Publications
Assessment of a protein cocktail-based skin test for bovine tuberculosis in a double-blind field test in cattle. Xin T, Jia H, Ding J, Li P, Yang H, Hou S, Yuan W, Guo X, Wang H, Liang Q, Li M, Wang B, Zhu H. Clin Vaccine Immunol. 2013 Apr;20(4):482-90. doi: 10.1128/CVI.00592-12. Epub 2013 Jan 30. (corresponding author).
CpG-enriched plasmid enhances the efficacy of the traditional foot-and-mouth disease killed vaccine. Guo X, Jia H, Zhang Q, Yuan W, Zhu G, Xin T, Zhu H, Sánchez-Vizcaíno JM. Microbiol Immunol. 2012 Feb 15. doi: 10.1111/j.1348-0421.2012.00438.x. (corresponding author).
Plasmid containing CpG motifs enhances the efficacy of porcine reproductive and respiratory syndrome live attenuated vaccine. Guo X, Zhang Q, Hou S, Zhai G, Zhu H, Sánchez-Vizcaíno JM. Vet Immunol Immunopathol. 2011 Dec 15;144(3-4):405-9. Epub 2011 Aug 4. (corresponding author).
Deletion of the Meq gene significantly decreases immunosuppression in chickens caused by pathogenic Marek's disease virus. Li Y, Sun A, Su S, Zhao P, Cui Z, Zhu H. Virol J. 2011 Jan 5;8:2. (corresponding author).
Plasmid containing CpG oligodeoxynucleotides can augment the immune responses of pigs immunized with porcine reproductive and respiratory syndrome killed virus vaccine. Quan Z, Qin ZG, Zhen W, Feng XZ, Hong J, Fei ZH. Vet Immunol Immunopathol. 2010 Aug 15;136(3-4):257-64. Epub 2010 Mar 25. (corresponding author).