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赵桂苹

个人信息

赵桂苹,女,1971年4月生,动物遗传育种与繁殖专业博士,研究员,博士生导师。国家“万人计划”科技创新领军人才、“国家百千万人才工程”有突出贡献国家中青年专家、中国农业科学院农科英才、广东省珠江学者讲座教授。中国畜牧兽医学会家禽学分会、遗传育种学分会理事;《全国肉鸡遗传改良计划(2014-2025)》专家组成员。

研究方向和成果

主要从事家禽育种工作,研究方向为肉鸡免疫抗病、肌肉品质的遗传机理与选育技术研究。建立了肌肉肌内脂肪含量、淋巴细胞比率为主选性状的选育技术,实现了肉质抗病等难以度量性状的遗传选择;研究定制出我国第一款鸡55K SNP芯片,构建肉鸡全基因组选择技术平台;获得育种技术国家发明专利5项,成功培育肉鸡新品种3个。制定了《肉鸡标准化养殖场》等国家和行业标准4项。参与肉鸡遗传改良计划方案起草、核心育种场和扩繁场遴选;作为主要执笔人编写了《动物种业科技创新战略研究报告》等战略报告。
研究成果先后荣获:
2016年国家科技进步二等奖“节粮优质抗病黄羽肉鸡新品种培育与应用” (排名第二);
2015年中华农业科技一等奖“黄羽肉鸡节粮、优质和抗病新品系选育关键技术及应用”(排名第二);
2010年获全国农牧渔业丰收一等奖“北方地区优质黄羽肉鸡新品种推广”(排名第三)。

在研项目

1. 主持“十三五”国家科技支撑计划项目课题“鸡种质资源培育与创新利用”(编号:2015BAD03B03)
2. 主持“十二五”国家科技支撑计划项目课题“优质高效肉鸡新品种选育及产业化示范”(编号:2011BAD28B0301)
3. 主持国家自然基金面上项目“靶向microRNA、LncRNA调控鸡先天免疫MyD88-依赖通路的抗菌机制(编号:31572393)
4. 主持“白羽肉鸡基因芯片定制和全基因组选择技术开发与应用”(编号:2016110014000091)

代表性论文和专利

专利:

1. 一种小型白羽肉鸡的三系配套制种方法(ZL 2015 1 0333980.1)

2. 与鸡胸肌重和胸肌率相关的SNP分子标记及其应用(ZL 2015 1 0070494.5)

3. 一种与鸡腹脂沉积相关的miRNA及其应用(ZL 2015 1 0494475.5)

4. 利用微卫星标记鉴定北京油鸡的方法(ZL201210133458.5)

5. 鸡抗病新品系的培育方法及与鸡抗病能力相关的SNP标记(ZL2014 1 0654722.9)

共发表论文70余篇,其中SCI 41篇;执行主编《动物种业科技创新战略研究报告》(131万字,科学出版社);主编《养鸡致富综合配套新技术》(28.5万字,中国农业出版社);副主编《专家与成功养殖者共谈-现代高效肉鸡养殖实战方案》(30万字,金盾出版社);参编《畜禽健康养殖》(40万字,中国农业科技出版社);主编《肉鸡体系工作简报》

代表性论文:

1. Liu RR, Xing SY, Wang J, Zheng MQ, Cui HX, Richard P. M. A. Crooijmans, Li QH, Zhao GP*, and Wen J*. A new chicken 55K SNP genotyping array. BMC genomics. 2019, 20:410.

2. Wang Q, Liu RR, Li QH, Wang F, Zhu Bo, Zheng MQ, Cui HX, Wen J, and Zhao GP*. Host Cell Interactome of PB1 N40 Protein of H5N1 Influenza A Virus in Chicken cells. Journal of Proteomics. 2019, 197:34-41.

3. Wang Q, Li QH, Liu T, Chang GB, Sun ZH, Gao Z, Wang F, Zhou HJ, Liu RR, Zheng MQ, Cui HX, Chen GH, Li H, Yuan XY, Wen J, Peng DX*, and Zhao GP* Host Interaction Analysis of PA-N155 and PA-N182 in Chicken Cells Reveals an Essential Role of UBA52 for Replication of H5N1 Avian Influenza Virus. Frontiers in Microbiology, 2018, 9(936):1

4. Wang Q, Li QH, Liu RR, Zheng MQ, Wen J, and Zhao GP* . Host cell interactome of PA protein of H5N1 influenza A virus in chicken cells. Journal of Proteomics. 2016,136:48-54.

5. Li P , Fan WL, Li QH , Wang J, Liu RR, Everaert N, Liu J, Zhang YH, Zheng MQ, Cui HC, Zhao GP*, and Wen J*. Splenic microRNA Expression Profiles and Integration Analyses. Frontiers in Cellular and Infection Microbiology. 2017, 7(1):377

6. Li QH, Yuan XY, Wang Q, Chang GB, Wang F, Liu RR, Zheng MQ, Chen GH, Wen J, and Zhao GP*. Interactomic landscape of PA-X-chicken protein complexes of H5N1 influenza A virus. Journal of Proteomics. 2016, 148:20-25

7. Zhang L, Li P, Liu RR, Zheng MQ, Sun YF, Wu D, HuYD, Wen J, and Zhao GP*. The identification of loci for immunetraits in chickens using a genome-wide association study, (2015), 3.30, PLoS ONE

8. Sun YF, Zhao GP#,Liu RR, Zheng MQ, Hu YD, Wu D, Zhang L, Li P, and Wen J*. The identification of 14 new genes for meat quality traits in chicken using a genome-wide. BMC genomics. 2013, 14: 458.

9. Zhou W, Liu RR, Zhang JJ, Zheng MQ, Chang GB, Li P, Wen J, Zhao GP*. A genome-wide detection of copy number variation using SNP genotyping arrays in Beijing-You chickens. Genetica (2014) 142:441–450

10. Cui HX, Zhao GP#, Liu RR, Zheng MQ, Chen J, Wen J. FSH stimulates lipid biosynthesis in chicken adipose tissue by up-regulating the expression of its receptor FSHR. The Journal of Lipid Research. 2012 53:(5) 909-917

11. Liu RR, Wang HY, Liu J, Wang J, Zheng MQ, Tan XD, Xing SY, Cui HX, Li QH, Zhao GP*,Wen J*. Uncovering the embryonic developmentrelated proteome and metabolome signatures in breast muscle and intramuscular fat of fast-and slow-growing chickens. BMC genomics. 2017 18:816

12. Li P1, Xia P, Wen J, Zheng MQ, Chen JL, Zhao J, Jiang RR, Liu RR, Zhao GP*.Up-regulation of the MyD88-dependent pathway of TLR signaling in spleen and caecum of young chickens infected with S P. Veterinary Microbiology. 2010 (143) 346–51.

13. Zhao GP#, Chen JL, Zheng MQ, Wen J, Zhang Y. Correlated responses to selection for increased intramuscular fat in a Chinese quality chicken line. Poultry Science. 2007(86): 2309-14.

联系方式

联系电话:010-62816019    E-mail:zhaoguiping@caas.cn